Fesoterodine (PF-00695838) | mAChR antagonist | Probechem Biochemicals

Chemical Structure : Fesoterodine

CAS No.: 286930-02-7

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Fesoterodine (PF-00695838, PF 00695838)

货号: PC-61891Not For Human Use, Lab Use Only.

Fesoterodine (PF-00695838) is a competitive muscarinic receptor antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors.

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生物&药学活性

Fesoterodine (PF-00695838) is a competitive muscarinic receptor antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors.

Fesoterodine has muscle relaxant and urinary antispasmodic properties.

Fesoterodine binds and inhibits muscarinic receptors on the bladder detrusor muscle, prevents bladder contractions or spasms caused by acetylcholine.

物理化学性质&存储条件

分子量	411.278
分子式	C26H37NO3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	[2-[(1R)-3-[di(propan-2-yl)amino]-1-phenylpropyl]-4-(hydroxymethyl)phenyl] 2-methylpropanoate

参考文献

1. Ney P, et al. BJU Int. 2008 Apr;101(8):1036-42.

2. Michel MC. Expert Opin Pharmacother. 2008 Jul;9(10):1787-96.

3. Chapple CR, et al. BJU Int. 2008 Nov;102(9):1128-32.

Fesoterodine (PF-00695838, PF 00695838)

生物&药学活性

物理化学性质&存储条件

参考文献

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Fesoterodine (PF-00695838, PF 00695838)

生物&药学活性

物理化学性质&存储条件

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