Fam20C inhibitor 3r

Chemical Structure : Fam20C inhibitor 3r

CAS No.: 2615358-19-3

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货号: PC-49525Not For Human Use, Lab Use Only.

Fam20C inhibitor 3r is a novel small-molecule inhibitor of Fam20C that induces apoptosis and inhibits migration in triple negative breast cancer.

规格	价格	库存
5 mg	￥2280	In stock
10 mg	￥3580	In stock
25 mg	￥5480	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

Fam20C inhibitor 3r is a novel small-molecule inhibitor of Fam20C that induces apoptosis and inhibits migration in triple negative breast cancer.
Fam20C inhibitor 3r has strong anti-proliferative activity in MDA-MB-231 cells, with an IC50 = 5.986 μM.
Fam20C inhibitor 3r induces apoptosis and exerts obvious anti-migration activity in MDA-MB-231 cells.
Fam20C inhibitor 3r has good therapeutic potential in TNBC xenograft model without apparent toxicity.

物理化学性质&存储条件

分子量	537.59
分子式	C26H27N5O6S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-methoxy-N-(4-((4-((3,4,5-trimethoxyphenyl)amino)pyrimidin-2-yl)amino)phenyl)benzenesulfonamide

参考文献

1. Rongyan Zhao, et al. Eur J Med Chem. 2021 Jan 15;210:113088.