FPFT-2216 | KZF1 and CK-1α degrader | Probechem Biochemicals

Chemical Structure : FPFT-2216

CAS No.: 2367619-87-0

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FPFT-2216 (FPFT2216)

货号: PC-20149Not For Human Use, Lab Use Only.

FPFT-2216 (FPFT2216) is a thalidomide derivative cereblon modulator that shows an inhibitory effect toward IKZF1 protein level, upregulates the production of IL-2 and degrades IKZF1 as well as CK-1α among ubiquitin–proteasomal degradative substrates of IMiDs.

规格	价格	库存
5 mg	￥2880	In stock
10 mg	￥4580	In stock
25 mg	￥7580	In stock
100 mg		Get quote
1 g		Get quote

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生物&药学活性

FPFT-2216 (FPFT2216) is a thalidomide derivative cereblon modulator that shows an inhibitory effect toward IKZF1 protein level, upregulates the production of IL-2 and degrades IKZF1 as well as CK-1α among ubiquitin–proteasomal degradative substrates of IMiDs.

物理化学性质&存储条件

分子量	262.29
分子式	C11H10N4O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-[4-(4-Methoxy-3-thienyl)-1H-1,2,3-triazol-1-yl]-2,6-piperidinedione

参考文献

1. Mingxing Teng, et al. J Med Chem. 2022 Jan 13;65(1):747-756.

2. Gemechu Y,et al. Proc Natl Acad Sci U S A. 2018 Nov 13;115(46):11802-11807.

FPFT-2216 (FPFT2216)

生物&药学活性

物理化学性质&存储条件

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FPFT-2216 (FPFT2216)

生物&药学活性

物理化学性质&存储条件

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