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首页-小分子抑制剂&激动剂-Immunology/Inflammation-NOD-like Receptor (NLR)-Emlenoflast
Emlenoflast

Chemical Structure : Emlenoflast

CAS No.: 1995067-59-8

Emlenoflast (MCC7840, Inzomelid, IZD174, MCC-7840)

货号: PC-73215Not For Human Use, Lab Use Only.

Emlenoflast (MCC7840, Inzomelid, IZD174) is a potent and selective inhibitor of NLRP3 inflammasome with IC50 of <100 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Emlenoflast (MCC7840, Inzomelid, IZD174) is a potent and selective inhibitor of NLRP3 inflammasome with IC50 of <100 nM.

物理化学性质&存储条件

分子量 388.486
分子式 C19H24N4O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-[[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl) amino]carbonyl]-1-(1-methylethyl)-1H-Pyrazole-3-sulfonamide

参考文献

1. Lina Y El-Sharkawy, et al. Molecules. 2020 Nov 25;25(23):5533.

2. O’Neill L. et al. WO/2016/131098.

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