Chemical Structure : Econazole nitrate
CAS No.: 24169-02-6
货号: PC-27956Not For Human Use, Lab Use Only.
Econazole nitrate is an imidazole derivative broad-spectrum antifungal agent, inhibits lanosterol 14α-demethylase, a key enzyme in the ergosterol synthesis pathway, also is a Ca2+ channel antagonist, induces cytotoxicity in leukemia cells, induces p53-dependent apoptosis and decreases metastasis ability in gastric cancer cells.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 g | ¥450 | In stock | |
| 10 mg | ¥750 | In stock | |
| 25 g | Get quote |
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Econazole nitrate is an imidazole derivative broad-spectrum antifungal agent, inhibits lanosterol 14α-demethylase, a key enzyme in the ergosterol synthesis pathway, also is a Ca2+ channel antagonist, induces cytotoxicity in leukemia cells, induces p53-dependent apoptosis and decreases metastasis ability in gastric cancer cells.
| 分子量 | 444.69 | |
| 分子式 | C18H16Cl3N3O4 | |
| 外观性状 | Solid | |
| 储存条件 |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
1-(2-((4-Chlorobenzyl)oxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole nitrate |
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1. Thienpont D, et al. Arzneimittelforschung. 1975 Feb;25(2):224-30.
2. Heel RC, et al. Drugs. 1978 Sep;16(3):177-201.
3. Choi EK, et al. Biomol Ther (Seoul). 2020 Jul 1;28(4):370-379.
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