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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Parasite-ELQ-596
ELQ-596

Chemical Structure : ELQ-596

CAS No.: 3023709-98-7

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ELQ-596 (ELQ596)

货号: PC-22513Not For Human Use, Lab Use Only.

ELQ-596 is a endochin-like quinolone compound with potent antibabesial activity with IC50 of 32 nM against B. duncani in human erythrocytes.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

ELQ-596 is a endochin-like quinolone compound with potent antibabesial activity with IC50 of 32 nM against B. duncani in human erythrocytes.
ELQ-596 display no cytotoxity against human cell lines: HeLa, HepG2, HEK293, and HCT116 (IC50>10 uM).

物理化学性质&存储条件

分子量 459.85
分子式 C24H17ClF3NO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

6-chloro-7-methoxy-2-methyl-3-(4'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl)quinolin-4(3H)-one

参考文献

1. Pratap Vydyam, et al. ACS Infect Dis. 2024 Apr 12;10(4):1405-1413.

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