E-5842 hydrochloride |CAS:177945-45-8 Probechem Biochemicals

Chemical Structure : E-5842 hydrochloride

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E-5842 hydrochloride (E5842)

货号: PC-63204Not For Human Use, Lab Use Only.

E-5842 is a preferential sigma-1 receptor ligand, demonstrates potential atypical antipsychotic effects in vivo.

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生物&药学活性

E-5842 hydrochloride (E5842) is a preferential sigma-1 receptor ligand, demonstrates potential atypical antipsychotic effects in vivo.
E-5842 increases phospholipase C (PLC) activity in the striatum and the hippocampus, increased levels of Fos in the medial prefrontal cortex and the nucleus accumbens in rat forebrain.

物理化学性质&存储条件

分子量	336.839
分子式	C17H22ClFN4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-(1H-1,2,4-triazol-1-yl)butyl)-4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridine hydrochloride

参考文献

1. Sánchez-Arroyos R, et al. Eur J Pharmacol. 1999 Jul 28;378(1):31-7.

2. Romero G, et al. Neurosci Lett. 2000 Sep 1;290(3):189-92.

3. Guitart X, et al. Neuropsychopharmacology. 2000 Nov;23(5):539-46.

4. Guitart X, et al. Eur J Pharmacol. 1998 Dec 18;363(2-3):127-30.

E-5842 hydrochloride (E5842)

生物&药学活性

物理化学性质&存储条件

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E-5842 hydrochloride (E5842)

生物&药学活性

物理化学性质&存储条件

参考文献

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