Darifenacin | CHI3L1 inhibitor, M3 mAChR inhibitor | Probechem Biochemicals

Chemical Structure : Darifenacin

CAS No.: 133099-04-4

加入收藏

Darifenacin (UK-88525, UK88525)

货号: PC-23023Not For Human Use, Lab Use Only.

Darifenacin (UK-88525) is a potent, selective M3 muscarinic receptor antagonist with pKi of 8.9, also inhibits CHI3L1(Chitinase 3-like 1) and PDAC cell growth.

规格	价格	库存
10 mg	￥780	In stock
25 mg	￥1380	In stock
50 mg	￥2380	In stock
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Darifenacin (UK-88525) is a potent, selective M3 muscarinic receptor antagonist with pKi of 8.9, also inhibits CHI3L1(Chitinase 3-like 1) and PDAC cell growth.
Darifenacin (UK-88525) exerts non-parallel rightward displacement of the agonist curve and also significant depression of the maximum response (+)-cis-Dioxolane produced concentration-dependent contraction of the isolated bladder of rats.
Darifenacin (UK-88525) sensitized PDAC cells to standard chemotherapies.

物理化学性质&存储条件

分子量	426.56
分子式	C28H30N2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-Pyrrolidineacetamide, 1-[2-(2,3-dihydro-5-benzofuranyl)ethyl]-α,α-diphenyl-, (3S)-

参考文献

1. Hegde SS, et al. Br J Pharmacol, 1997, 120(8), 1409-1418.

2. Sousa SM, et al. Cancer Chemother Pharmacol. 2024 Sep 3. doi: 10.1007/s00280-024-04712-1.

Darifenacin (UK-88525, UK88525)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Darifenacin (UK-88525, UK88525)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.