DW18343

Chemical Structure : DW18343

加入收藏

货号: PC-23719Not For Human Use, Lab Use Only.

DW18343 is a specific, non-nucleotide stimulator of interferon genes (STING) agonist, binds to the LBD region of the STING protein, exhibits broad‐spectrum antitumor acitvity.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

DW18343 is a specific, non-nucleotide stimulator of interferon genes (STING) agonist, binds to the LBD region of the STING protein, exhibits broad‐spectrum antitumor acitvity.
DW18343 demonstrates more robust activation of the STING‐H232 subtype when compared to S100.
DW18343 activates the STING downstream signaling pathway, triggers downstream p‐TBK1/p‐IRF3 signaling, leading to the production of multiple cytokines.
DW18343 exhibits broad‐spectrum antitumor effect.
DW18343 stimulates the development of antitumor immune memory in mice.

物理化学性质&存储条件

分子量	317.33
分子式	C16H12FNO3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(4-(7-fluoro-1H-indol-3-yl)thiophen-2-yl)-4-oxobutanoic acid

参考文献

1. Wang X, et al. MedComm (2020). 2024 Dec 20;6(1):e70001.

DW18343

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

DW18343

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.