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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Parasite-DNDI-0690
DNDI-0690

Chemical Structure : DNDI-0690

CAS No.: 2097881-13-3

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DNDI-0690 (DNDI-0690, DNDI 0690 )

货号: PC-25291Not For Human Use, Lab Use Only.

DNDI-0690 is a clinical drug candidate for visceral leishmaniasis (VL), demonstrated excellent in vitro activity against three Old World and three New World cutaneous Leishmania strains (EC50<5 uM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

DNDI-0690 is a clinical drug candidate for visceral leishmaniasis (VL), demonstrated excellent in vitro activity against three Old World and three New World cutaneous Leishmania strains (EC50<5 uM).

物理化学性质&存储条件

分子量 370.34
分子式 C18H15FN4O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(R)-7-(((6-(4-fluorophenyl)pyridin-3-yl)oxy)methyl)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine

参考文献

1. Van Bocxlaer K, et al. Int J Parasitol Drugs Drug Resist. 2019 Dec;11:129-138.

2. Wijnant GJ, et al. Antimicrob Agents Chemother. 2019 Aug 23;63(9):e00829-19.

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