NVP-DFV890 (IFM-2427) | NLRP3 inhibitor | Probechem Biochemicals

Chemical Structure : DFV890

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DFV890 (NVP-DFV890, DFV-890, IFM-2427, IFM2427)

货号: PC-21282Not For Human Use, Lab Use Only.

DFV890 (NVP-DFV890, IFM-2427) is a potent, selective and orally active inhibitor of NLRP3 inflammasome, directly binds to NLRP3 and locks the protein in an inactive conformation, prevents NLRP3 inflammasome assembly in response to sterile danger signals.

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DFV890 (NVP-DFV890, IFM-2427) is a potent, selective and orally active inhibitor of NLRP3 inflammasome, directly binds to NLRP3 and locks the protein in an inactive conformation, prevents NLRP3 inflammasome assembly in response to sterile danger signals.

物理化学性质&存储条件

分子量	420.55
分子式	C19H24N4O3S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-N'-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-2-(2-hydroxypropan-2-yl)thiazole-5-sulfonimidamide

参考文献

1. Patent WO2020010118A1.

DFV890 (NVP-DFV890, DFV-890, IFM-2427, IFM2427)

生物&药学活性

物理化学性质&存储条件

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DFV890 (NVP-DFV890, DFV-890, IFM-2427, IFM2427)

生物&药学活性

物理化学性质&存储条件

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