Cridanimod (10-CMA, XBIO-101)

Chemical Structure : Cridanimod

CAS No.: 38609-97-1

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货号: PC-60186Not For Human Use, Lab Use Only.

Cridanimod (10-CMA, XBIO-101) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.

规格	价格	库存
10 mg	￥980	In stock
25 mg	￥1580	In stock
50 mg	￥2480	In stock
100 mg		Get quote

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生物&药学活性

Cridanimod (10-CMA, XBIO-101) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.
Cridanimod displays extraordinary activity in phosphorylating IRF3 in the murine system.
Cridanimod also increases progesterone receptor (PrR) expression in endometrial tissue.

物理化学性质&存储条件

分子量	253.25
分子式	C15H11NO3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(9-oxoacridin-10-yl)acetic acid

参考文献

1. Cavlar T, et al. EMBO J. 2013 May 15;32(10):1440-50.

2. Zhang H, et al. Sci Rep. 2015 Dec 16;5:18035.