Cevimeline hydrochloride |CAS:107220-28-0 Probechem Biochemicals

Chemical Structure : Cevimeline hydrochloride

CAS No.: 107220-28-0

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Cevimeline hydrochloride (AF-102B hydrochloride;SNI-2011 hydrochloride)

货号: PC-45939Not For Human Use, Lab Use Only.

Cevimeline hydrochloride is a potent M1-selective muscarinic agonist.

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生物&药学活性

Cevimeline hydrochloride is a potent M1-selective muscarinic agonist.
Cevimeline decreases the K+-evoked [3H]ACh release from hippocampal synaptosomes and increases the K+-evoked [3H]DA release from striatal synaptosomes.
Cevimeline attenuates cognitive dysfunctions in AF64A-treated rats with low toxicity.

物理化学性质&存储条件

分子量	235.774
分子式	C10H18ClNOS
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane], 2'-methyl-, hydrochloride (1:1), (2'R,3R)-rel-

参考文献

1. Ono S, et al. Eur J Pharmacol. 1988 Oct 11;155(1-2):77-84.

2. Fisher A, et al. Neurosci Lett. 1989 Jul 31;102(2-3):325-31.

3. Nakahara N, et al. Jpn J Pharmacol. 1989 Dec;51(4):539-47.

Cevimeline hydrochloride (AF-102B hydrochloride;SNI-2011 hydrochloride)

生物&药学活性

物理化学性质&存储条件

参考文献

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Cevimeline hydrochloride (AF-102B hydrochloride;SNI-2011 hydrochloride)

生物&药学活性

物理化学性质&存储条件

参考文献

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