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首页-小分子抑制剂&激动剂-GPCR-Lysophospholipid Receptor-CYM-5541
CYM-5541

Chemical Structure : CYM-5541

CAS No.: 945128-26-7

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CYM-5541 (ML249, CYM5541, CYM 5541)

货号: PC-42379Not For Human Use, Lab Use Only.

CYM-5541 (ML249) is a potent, selective, allosteric and full agonist of S1P3 receptor with EC50 of 72-132 nM.

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10 mg ￥980 In stock
25 mg ￥1680 In stock
50 mg ￥2680 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CYM-5541 (ML249) is a potent, selective, allosteric and full agonist of S1P3 receptor with EC50 of 72-132 nM.
CYM-5541 exhibits exquisite selectivity over other S1P receptor subtypes in vitro (EC50>10 uM), also shows no significant activities against panel of 55 GPCRs, ion channels, and transporters.

物理化学性质&存储条件

分子量 316.43782
分子式 C19H28N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 39 mg/mL
Chemical Name/SMILES

3-Isoxazolecarboxamide, N,N-dicyclohexyl-5-cyclopropyl-

参考文献

1. Jo E, et al. ACS Chem Biol. 2012 Dec 21;7(12):1975-83.

2. St-Cyr Giguère F, et al. Brain Res. 2017 Mar 1;1658:51-59.

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