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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Parasite-CTN1122
CTN1122

Chemical Structure : CTN1122

CAS No.: 1809980-64-0

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CTN1122 (CTN-1122)

货号: PC-72407Not For Human Use, Lab Use Only.

CTN1122 (CTN-1122) is a potent, selective Leishmaniacasein kinase 1 isoform 2 (CK1.2, L-CK1.2) with IC50 of 0.72 uM (LmCK1) and 0.8 uM (amastigotes L. major), antileishmanial compound.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    CTN1122 (CTN-1122) is a potent, selective Leishmaniacasein kinase 1 isoform 2 (CK1.2, L-CK1.2) with IC50 of 0.72 uM (LmCK1) and 0.8 uM (amastigotes L. major), antileishmanial compound.

    物理化学性质&存储条件

    分子量 333.37
    分子式 C19H16FN5
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-(4-fluorophenyl)-N,N-dimethyl-3-(pyridin-4-yl)imidazo[1,2-a]pyrazin-8-amine

    参考文献

    1. Marc-Antoine Bazin, et al. Eur J Med Chem. 2021 Jan 15;210:112956.

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