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首页-抗体药物偶连体和PROTACs-PROTAC-CST967
CST967

Chemical Structure : CST967

CAS No.:

CST967 (CST-967)

货号: PC-22884Not For Human Use, Lab Use Only.

CST967 is a potent selective USP7 PROTAC degrader with DC50 of 17 nM, Dmax of 84% in MM.1S cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CST967 is a potent selective USP7 PROTAC degrader with DC50 of 17 nM, Dmax of 84% in MM.1S cells.

物理化学性质&存储条件

分子量 927.07
分子式 C51H58N8O9
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(1-(1-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)piperidine-4-carbonyl)piperidin-4-yl)-N-(3-((4-hydroxy-1-((R)-3-phenylbutanoyl)piperidin-4-yl)methyl)-4-oxo-3,4-dihydroquinazolin-7-yl)propanamide

参考文献

1. Arunima Murgai, et al. Chem Commun (Camb). 2022 Aug 4;58(63):8858-8861.

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