CS-0777 |CAS:827344-05-8 Probechem Biochemicals

Chemical Structure : CS-0777

加入收藏

CS-0777 (CS 0777;CS0777)

货号: PC-61014Not For Human Use, Lab Use Only.

CS-0777 is a potent, selective, orally active S1P receptor-1 (S1P1) agonist with EC50 of 1.1 nM, 320-fold selectivity over S1P3.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

CS-0777 is a potent, selective, orally active S1P receptor-1 (S1P1) agonist with EC50 of 1.1 nM, 320-fold selectivity over S1P3.
CS-0777 significantly decreases lymphocyte counts at doses of 0.1 and 1 mg/kg in rats, demonstrates potential benefits in the treatment of autoimmune diseases.

物理化学性质&存储条件

分子量	342.483
分子式	C21H30N2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-1-(5-(3-amino-4-hydroxy-3-methylbutyl)-1-methyl-1H-pyrrol-2-yl)-4-(p-tolyl)butan-1-one

参考文献

1. Nishi T, et al. ACS Med Chem Lett. 2011 Mar 2;2(5):368-72.

2. Yonesu K, et al. J Biol Chem. 2011 Jul 15;286(28):24765-75.

3. Moberly JB, et al. J Neuroimmunol. 2012 May 15;246(1-2):100-7.

4. Inaba S, et al. Xenobiotica. 2015;45(12):1063-80.

CS-0777 (CS 0777;CS0777)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

CS-0777 (CS 0777;CS0777)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.