CPD-2828 | IRE1α PROTAC | Probechem Biochemicals

Chemical Structure : CPD-2828

加入收藏

货号: PC-25907Not For Human Use, Lab Use Only.

CPD-2828 is the first PROTAC degrader of IRE1α with DC50 of 0.43 uM in HEK293T cell, exhibits CRBN binding IC50 of 0.65 uM.

获取报价单

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

CPD-2828 is the first PROTAC degrader of IRE1α with DC50 of 0.43 uM in HEK293T cell, exhibits CRBN binding IC50 of 0.65 uM.

分子量	531.57
分子式	C29H29N3O7
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(2-(4-(4-((2,6-dioxopiperidin-3-yl)amino)phenyl)piperidin-1-yl)-2-oxoethyl)-7-hydroxy-4-methyl-2-oxo-2H-chromene-8-carbaldehyde

1. Zerfas BL, et al. RSC Med Chem. 2025 Mar 18. doi: 10.1039/d5md00028a.