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CMLD009688

Chemical Structure : CMLD009688

CAS No.:

CMLD009688

货号: PC-24877Not For Human Use, Lab Use Only.

CMLD009688 is a growth inhibitor of Fusarium graminearum with MIC of 12.5-50 uM, acts as a cationic amphiphilic compound to inhibit F. graminearum conidial germination in a fungicidal manner.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CMLD009688 is a growth inhibitor of Fusarium graminearum with MIC of 12.5-50 uM, acts as a cationic amphiphilic compound to inhibit F. graminearum conidial germination in a fungicidal manner.
CMLD009688 impacts vacuolar and mitochondrial membrane integrity at inhibitory and subinhibitory concentrations.
CMLD009688 disrupts vacuolar and mitochondrial morphology in F. graminearum.
CMLD009688 synergistically destabilizes the fungal vacuole alongside pyraclostrobin.
CMLD009688 is effective against F. graminearum and B. cinerea in relevant models of plant infection.

物理化学性质&存储条件

分子量 387.52
分子式 C26H29NO2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(1S,2R,3S)-6-methoxy-2-methyl-N-(3-phenoxypropyl)-3-phenyl-2,3-dihydro-1H-inden-1-amine

参考文献

1. Laflamme B, et al. Cell Chem Biol. 2025 Jun 19;32(6):872-884.e7.

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