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首页-小分子抑制剂&激动剂-Wnt/Notch/Hedgehog-Casein Kinase-CK1-IN-3c
CK1-IN-3c

Chemical Structure : CK1-IN-3c

CAS No.: 756805-89-7

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CK1-IN-3c

货号: PC-62834Not For Human Use, Lab Use Only.

CK1-IN-3c is a novel casein kinase 1δ/ε (CK1δ/ε) inhibitor with IC50 of 1.6 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    CK1-IN-3c is a novel casein kinase 1δ/ε (CK1δ/ε) inhibitor with IC50 of 1.6 uM.
    CK1-IN-3c shows selectivity over CDK5/p25, GSK-3α/β, and DYRK1A.
    CK1-IN-3c elicits selective cytotoxic activity against the PANC-1 cell line.

    物理化学性质&存储条件

    分子量 347.378
    分子式 C19H17N5O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    6,7-dimethoxy-N-(5-phenyl-1H-pyrazol-3-yl)quinazolin-4-amine

    参考文献

    1. Karthikeyan C, et al. Bioorg Med Chem Lett. 2017 Jun 15;27(12):2663-2667.

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