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首页-小分子抑制剂&激动剂-GPCR-mAChR-CHF-6550
CHF-6550

Chemical Structure : CHF-6550

CAS No.:

CHF-6550 (CHF6550)

货号: PC-22509Not For Human Use, Lab Use Only.

CHF-6550 is a potent, dual acting muscarinic M3 antagonist and β2 agonist (MABA) with pKi values of 9.3 and 10.6 for M3 and β2 receptor, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CHF-6550 is a potent, dual acting muscarinic M3 antagonist and β2 agonist (MABA) with pKi values of 9.3 and 10.6 for M3 and β2 receptor, respectively.

物理化学性质&存储条件

分子量 734.85
分子式 C42H46N4O8
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-1-methylpiperidin-3-yl (R)-2-hydroxy-2-(3-(3-(4-((((R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl)amino)methyl)benzamido)propoxy)phenyl)-2-phenylacetate

参考文献

1. Laura Carzaniga, et al. J Med Chem. 2024 Jun 10. doi: 10.1021/acs.jmedchem.4c00298.

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