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首页-小分子抑制剂&激动剂-GPCR-mAChR-CHF-6366
CHF-6366

Chemical Structure : CHF-6366

CAS No.: 1615208-41-7

CHF-6366 (CHF6366)

货号: PC-49312Not For Human Use, Lab Use Only.

CHF-6366 is a novel potent muscarinic antagonist and β2 agonist (MABA) with pKi of 10.2 and 11.4, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    CHF-6366 is a novel potent muscarinic antagonist and β2 agonist (MABA) with pKi of 10.2 and 11.4, respectively.

    物理化学性质&存储条件

    分子量 764.880
    分子式 C42H48N6O8
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-(((R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl)amino)butyl 1-methyl-5-((3-((S)-phenyl(((((R)-quinuclidin-3-yl)oxy)carbonyl)amino)methyl)phenoxy)methyl)-1H-pyrazole-3-carboxylate

    参考文献

    1. Laura Carzaniga, et al. J Med Chem. 2022 Aug 11;65(15):10233-10250.

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