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首页-抗体药物偶连体和PROTACs-PROTAC-CDK9 PROTAC 1
CDK9 PROTAC 1

Chemical Structure : CDK9 PROTAC 1

CAS No.: 2118356-96-8

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CDK9 PROTAC 1

货号: PC-60100Not For Human Use, Lab Use Only.

CDK9 PROTAC 1 is a heterobifunctional small molecule PROTAC capable of cereblon mediated proteasomal degradation of CDK9.

规格 价格 库存 数量
1 mg ￥1580 In stock
5 mg ￥2980 In stock
10 mg ￥4880 In stock
25 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CDK9 PROTAC 1 is a heterobifunctional small molecule PROTAC capable of cereblon mediated proteasomal degradation of CDK9.
CDK9 PROTAC 1 selectively degrades CDK9 while sparing other CDK family members in HCT116 cells.

物理化学性质&存储条件

分子量 613.671
分子式 C33H35N5O7
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(5-cyclobutyl-1H-pyrazol-3-yl)-2-(4-((5-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)pentyl)oxy)phenyl)acetamide

参考文献

1. Robb CM, et al. Chem Commun (Camb). 2017 Jul 4;53(54):7577-7580.

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