Chemical Structure : CCT400028
货号: PC-26015Not For Human Use, Lab Use Only.
CCT400028 is a second-generation alisertib-derived Aurora A PROTAC with DC50 of 29 nM in MV4-11 leukemia cells, D max=85%, shows excellent selectivity in proteomic and kinase selectivity profiling.
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CCT400028 is a second-generation alisertib-derived Aurora A PROTAC with DC50 of 29 nM in MV4-11 leukemia cells, D max=85%, shows excellent selectivity in proteomic and kinase selectivity profiling.
| 分子量 | 878.40 | |
| 分子式 | C47H49ClFN7O7 | |
| 外观性状 | Solid | |
| 储存条件 |
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| Solubility |
10 mM in DMSO |
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1. O'Hanlon JA, et al. J Med Chem. 2026 Jan 22;69(2):1552-1567.
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