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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Fungal-Butenafine hydrochloride
Butenafine hydrochloride

Chemical Structure : Butenafine hydrochloride

CAS No.: 101827-46-7

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Butenafine hydrochloride (KP363 hydrochloride)

货号: PC-45219Not For Human Use, Lab Use Only.

A synthetic benzylamine antifungal that inhibits the synthesis of ergosterol by inhibiting squalene epoxidase.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Butenafine (KP363) is a synthetic benzylamine antifungal that inhibits the synthesis of ergosterol by inhibiting squalene epoxidase.
Butenafine displays superior activity against Candida albicans than terbinafine and naftifine.
Butenafine demonstrates low MICs against Cryptococcus and Aspergillus.

物理化学性质&存储条件

分子量 353.9281
分子式 C23H28ClN
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-Naphthalenemethanamine, N-[[4-(1,1-dimethylethyl)phenyl]methyl]-N-methyl-, hydrochloride (1:1)

参考文献

1. Singal A. Expert Opin Drug Metab Toxicol. 2008 Jul;4(7):999-1005.

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