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首页-小分子抑制剂&激动剂-Tyrosine Kinase-Trk Receptor-Boditrectinib
Boditrectinib

Chemical Structure : Boditrectinib

CAS No.: 1940165-80-9

Boditrectinib (AUM-601, NOV1601, HL5101, CHC-2014)

货号: PC-20024Not For Human Use, Lab Use Only.

Boditrectinib (AUM-601, NOV1601, HL5101, CHC-2014) is a highly selective, orally administered, which inhibits not only pan-TRK (TRKA, TRKB, and TRKC), but also resistance mutations of TRKs.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Boditrectinib (AUM-601, NOV1601, HL5101, CHC-2014) is a highly selective, orally administered, which inhibits not only pan-TRK (TRKA, TRKB, and TRKC), but also resistance mutations of TRKs.

    物理化学性质&存储条件

    分子量 438.48
    分子式 C23H24F2N6O
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (R,E)-3-(5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-1-(piperazin-1-yl)prop-2-en-1-one

    参考文献

    1. Patent US20160168156.

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