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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Fungal-Bifonazole
Bifonazole

Chemical Structure : Bifonazole

CAS No.: 60628-96-8

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Bifonazole (Bay H-4502)

货号: PC-27949Not For Human Use, Lab Use Only.

Bifonazole (Bay H-4502) is an imidazole antifungal agent that inhibits ergosterol biosynthesis via specifically targets fungal lanosterol 14α-demethylase (CYP51A1), also is a SARS-CoV-2 blocking agent that binds ACE2 and prevents association with the RBD, affecting entry and replication of spike-pseudotyped viruses as well as native SARS-CoV-2 and its variants of concern (VOCs).

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250 mg ￥380 In stock
1 g ￥780 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Bifonazole (Bay H-4502) is an imidazole antifungal agent that inhibits ergosterol biosynthesis via specifically targets fungal lanosterol 14α-demethylase (CYP51A1), also is a SARS-CoV-2 blocking agent that binds ACE2 and prevents association with the RBD, affecting entry and replication of spike-pseudotyped viruses as well as native SARS-CoV-2 and its variants of concern (VOCs).

物理化学性质&存储条件

分子量 310.40
分子式 C22H18N2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-([1,1'-Biphenyl]-4-yl(phenyl)methyl)-1H-imidazole

参考文献

1. Barug D, et al. Arzneimittelforschung. 1983;33(4):524-8.

2. Taha Z, et al. Mol Ther. 2022 Sep 7;30(9):2998-3016.

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