BTK PROTAC degrader 3

Chemical Structure : BTK PROTAC degrader 3

加入收藏

货号: PC-22861Not For Human Use, Lab Use Only.

BTK PROTAC degrader 3 is a potent BTK degrader with DC50 value of 10.9 nM in Mino cells, shows potential for B-cell malignancies, including chronic lymphoid malignancies.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

BTK PROTAC degrader 3 is a potent BTK degrader with DC50 value of 10.9 nM in Mino cells, shows potential for B-cell malignancies, including chronic lymphoid malignancies.

物理化学性质&存储条件

分子量	752.82
分子式	C41H40N10O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-[3-[4-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl][1,3′-biazetidin]-1′-yl]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione

参考文献

1. Zhangchen, et al. Salt of compound for degrading btk, crystal form thereof, and use thereof in medicine. Patent WO2022052950A1.