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首页-小分子抑制剂&激动剂-Immunology/Inflammation-STING-BSP16
BSP16

Chemical Structure : BSP16

CAS No.: 2727249-47-8

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BSP16 (LF250)

货号: PC-49313Not For Human Use, Lab Use Only.

BSP16 (LF250) is a potent, orally available STING agonist, strongly activates STING signaling in human and mouse cells and binds STING as a homodimer.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    BSP16 is a potent, orally available STING agonist, strongly activates STING signaling in human and mouse cells and binds STING as a homodimer.
    BSP16 could induce the "closed" conformation of STING. has an excellent pharmacokinetic profile as an oral drug, and induces tumor regression and durable antitumor immunity

    物理化学性质&存储条件

    分子量 369.275
    分子式 C16H18O5Se
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (R)-4-(5,6-dimethoxybenzo[b]selenophen-2-yl)-2-ethyl-4-oxobutanoic acid

    参考文献

    1. Xi Feng, et al. J Med Chem. 2022 Sep 7. doi: 10.1021/acs.jmedchem.2c00634.

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