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首页-小分子抑制剂&激动剂-GPCR-Sigma Receptor-BS148
BS148

Chemical Structure : BS148

CAS No.: 2162116-09-6

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BS148 (BS-148)

货号: PC-35305Not For Human Use, Lab Use Only.

BS148 (BS-148) is a potent, selective σ2 receptor agonist with pKi of 7.71, displays 25-fold selectivity over σ1.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

BS148 (BS-148) is a potent, selective σ2 receptor agonist with pKi of 7.71, displays 25-fold selectivity over σ1.
BS148 specifically inhibits the growth of metastatic malignant melanoma cell lines without affecting normal human melanocytes.

物理化学性质&存储条件

分子量 361.606
分子式 C21H31NS2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(1,4-dithiaspiro[4.5]decan-2-ylmethyl)-4-benzylpiperidine

参考文献

1. Franchini S, et al. ChemMedChem. 2017 Nov 22;12(22):1893-1905.

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