BRD4 degrader AT1 | BRD4 PROTAC | Probechem Biochemicals

Chemical Structure : BRD4 degrader AT1

CAS No.: 2098836-45-2

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BRD4 degrader AT1 (BRD4 PROTAC AT1)

货号: PC-35351Not For Human Use, Lab Use Only.

BRD4 degrader AT1 is a highly selective BRD4 degrader (PROTAC), exhibits highly selective depletion of BRD4 in cells with negligible activity against BRD2 and BRD3.

规格	价格	库存
1 mg	￥1180	In stock
5 mg	￥2880	In stock
10 mg	￥4880	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

BRD4 degrader AT1 is a highly selective BRD4 degrader (PROTAC), exhibits highly selective depletion of BRD4 in cells with negligible activity against BRD2 and BRD3.

物理化学性质&存储条件

分子量	972.68
分子式	C48H58ClN9O5S3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S,4R)-1-((R)-2-acetamido-3-((6-(2-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetamido)hexyl)thio)-3-methylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide

参考文献

1. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.

BRD4 degrader AT1 (BRD4 PROTAC AT1)

生物&药学活性

物理化学性质&存储条件

参考文献

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BRD4 degrader AT1 (BRD4 PROTAC AT1)

生物&药学活性

物理化学性质&存储条件

参考文献

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