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首页-小分子抑制剂&激动剂-GPCR-Lysophospholipid Receptor-BMS-986278
BMS-986278

Chemical Structure : BMS-986278

CAS No.: 2170126-74-4

BMS-986278 (BMS986278)

货号: PC-72349Not For Human Use, Lab Use Only.

BMS-986278 (BMS986278) is a potent, selective lysophosphatidic acid receptor 1 (LPA1) antagonist with human LPA1 Kb of 6.9 nM.

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5 mg ¥2580 In stock
10 mg ¥3980 In stock
25 mg ¥5980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BMS-986278 (BMS986278) is a potent, selective lysophosphatidic acid receptor 1 (LPA1) antagonist with human LPA1 Kb of 6.9 nM.

物理化学性质&存储条件

分子量 445.52
分子式 C22H31N5O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Cyclohexanecarboxylic acid, 3-[[2-methyl-6-[1-methyl-5-[[[(methylpropylamino)carbonyl]oxy]methyl]-1H-1,2,3-triazol-4-yl]-3-pyridinyl]oxy]-, (1S,3S)-

参考文献

1. Cheng PTW, et al. J Med Chem. 2021 Nov 11;64(21):15549-15581.

2. Corte TJ, et al. BMJ Open Respir Res. 2021 Dec;8(1):e001026.

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