BDW568 | STING agonist | Probechem Biochemicals

Chemical Structure : BDW568

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BDW568 (BDW-568)

货号: PC-22431Not For Human Use, Lab Use Only.

BDW568 is a non-nucleotide agonist of human STING (stimulator of interferon genes) and type-I interferon signaling activator.

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生物&药学活性

BDW568 is a non-nucleotide agonist of human STING (stimulator of interferon genes) and type-I interferon signaling activator.
BDW568 could robustly activate the STING pathway in human primary peripheral blood mononuclear cells (PBMCs) with STINGA230 genotype from healthy individuals.
BDW568 could robustly activate type I interferon signaling in purified human primary macrophages that were transduced with lentivirus expressing STINGA230.

物理化学性质&存储条件

分子量	308.37
分子式	C12H12N4O2S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Methyl 2-[(8,9-dimethylthieno[3,2-e]-1,2,4-triazolo[4,3-c]pyrimidin-3-yl)thio]acetate

参考文献

1. Zhao J, et al. ACS Cent Sci. 2022 Oct 26;8(10):1424-1434.

2. Tang Z, et al. bioRxiv [Preprint]. 2023 Jul 10:2023.07.02.547363.

BDW568 (BDW-568)

生物&药学活性

物理化学性质&存储条件

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BDW568 (BDW-568)

生物&药学活性

物理化学性质&存储条件

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