BD-1063 dhydrochloride |CAS:206996-13-6 Probechem Biochemicals

Chemical Structure : BD-1063 dhydrochloride

CAS No.: 206996-13-6

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BD-1063 dhydrochloride (BD1063 dhydrochloride)

货号: PC-45420Not For Human Use, Lab Use Only.

BD-1063 dhydrochloride (BD1063) is a potent, selective sigma-1 receptor antagonist with binding Ki of 9 nM.

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10 mg	￥1080	In stock
25 mg	￥1880	In stock
50 mg	￥2980	In stock
100 mg		Get quote

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生物&药学活性

BD-1063 dhydrochloride (BD1063) is a potent, selective sigma-1 receptor antagonist with binding Ki of 9 nM.
BD-1063 displays >49-fold selectivity over the sigma-2 receptor.
BD-1063 significantly reverses the neuroprotective effect of DHEA-S against NMDA-induced neurotoxicity in rat hippocampal neurons.

物理化学性质&存储条件

分子量	346.1233
分子式	C13H20Cl4N2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	100 mM in H2O
Chemical Name/SMILES	Piperazine, 1-[2-(3,4-dichlorophenyl)ethyl]-4-methyl-, hydrochloride (1:2)

参考文献

1. Matsumoto RR, et al. Eur J Pharmacol. 2001 May 11;419(2-3):163-74.

2. Matsumoto RR, et al. Eur J Pharmacol. 1995 Jul 14;280(3):301-10.

3. Wu Z, et al. J Biol Chem. 2008 Oct 17;283(42):28198-215.

BD-1063 dhydrochloride (BD1063 dhydrochloride)

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物理化学性质&存储条件

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BD-1063 dhydrochloride (BD1063 dhydrochloride)

生物&药学活性

物理化学性质&存储条件

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