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BD-1047

Chemical Structure : BD-1047

CAS No.: 138356-20-4

BD-1047 (BD1047)

货号: PC-63070Not For Human Use, Lab Use Only.

BD-1047 is a potent, selecitve Sigma 1 receptor (σ1) antagonist with Ki of 0.93 nM.

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25 mg ¥1480 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BD-1047 is a potent, selecitve Sigma 1 receptor (σ1) antagonist with Ki of 0.93 nM.
BD-1047 displays 50-fold weaker affinity for sigma 2 receptor, and 100-fold selectivity over opiate, phencyclidine, muscarinic, dopamine, adrenoceptor and 5-HT receptors.
BD-1047 attenuates the dystonia induced by DTG and haloperidol in rats.

物理化学性质&存储条件

分子量 275.217
分子式 C13H20Cl2N2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamine

参考文献

1. Matsumoto RR, et al. Eur J Pharmacol. 1995 Jul 14;280(3):301-10.

2. Zambon AC, et al. Eur J Pharmacol. 1997 Apr 11;324(1):39-47.

3. Roh DH, et al. Anesthesiology. 2008 Nov;109(5):879-89.

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