Chemical Structure : BAL-0028
CAS No.: 2842012-69-3
货号: PC-22057Not For Human Use, Lab Use Only.
BAL-0028 (BAL0028) is a potent, selective and reversible inhibitor of NLRP3 activation with IC50 of 25 nM, binds to the NACHT domain of NLRP3 with Kd of 104-123 nM.
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---|---|---|---|
5 mg | ¥880 | In stock | |
10 mg | ¥1280 | In stock | |
25 mg | ¥2180 | In stock | |
50 mg | ¥3580 | In stock | |
100 mg | Get quote |
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BAL-0028 (BAL0028) is a potent, selective and reversible inhibitor of NLRP3 activation with IC50 of 25 nM, binds to the NACHT domain of NLRP3 with Kd of 104-123 nM.
BAL-0028 is distinct from MCC950 and includes specific site interactions.
分子量 | 403.46 | |
分子式 | C24H22FN3O2 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N-((1H-indazol-7-yl)methyl)-2-ethoxy-3'-fluoro-N-methyl-[1,1'-biphenyl]-4-carboxamide |
1. George Hartman, et al. Bioorg Med Chem Lett. 2024 Apr 1:102:129675.
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