Aureobasidin A | Antifungal antibiotic | Probechem Biochemicals

Chemical Structure : Aureobasidin A

CAS No.: 127785-64-2

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Aureobasidin A (AbA, LY295337, Basifungin)

货号: PC-73162Not For Human Use, Lab Use Only.

Aureobasidin A (AbA, Basifungin) is a cyclic depsipetide antifungal antibiotic, inhibits the inositolphosphorylceramide synthase AUR1.

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5 mg	￥2580	In stock
25 mg	￥6280	In stock
100 mg	￥15800	In stock
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生物&药学活性

Aureobasidin A (AbA, Basifungin) is a cyclic depsipetide antifungal antibiotic, inhibits the inositolphosphorylceramide synthase AUR1.
Aureobasidin A (AbA) arrests growth of yeast cells through both ceramide intoxication and deprivation of essential inositolphosphorylceramides.
Aureobasidin A (AbA) is highly active in vitro against many pathogenic fungi, including Candida albicans, Cryptococcus neoformans, Blastomyces dermatitidis and Histoplasma capsulatum.
Aureobasidin A (AbA) is highly tolerated by mice and showed good efficacy in the treatment of murine systemic candidiasis when given orally or subcutaneously.

物理化学性质&存储条件

分子量	1101.42
分子式	C60H92N8O11
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 Month
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Solubility
Chemical Name/SMILES

参考文献

1. Kino K, et al. FEBS Lett. 1996 Dec 9;399(1-2):29-32.

2. Hashida-Okado T, et al. Mol Gen Genet. 1996 May 23;251(2):236-44.

3. Takesako K, et al. J Antibiot (Tokyo). 1993 Sep;46(9):1414-20.

4. Heidler SA, et al. Antimicrob Agents Chemother. 1995 Dec;39(12):2765-9.

Aureobasidin A (AbA, LY295337, Basifungin)

生物&药学活性

物理化学性质&存储条件

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Aureobasidin A (AbA, LY295337, Basifungin)

生物&药学活性

物理化学性质&存储条件

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