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首页-抗体药物偶连体和PROTACs-PROTAC-AZ6421
AZ6421

Chemical Structure : AZ6421

CAS No.: 2361115-35-5

AZ6421 (AZ'6421)

货号: PC-49352Not For Human Use, Lab Use Only.

AZ'6421 is a Protcolysis Targeting Chimera (PROTAC) to selectively degrade estrogen receptor, shows ER binding and ER degradation with IC50 and DC50 values of 0.6 nM and 0.4 nM, respectively in MCF-7 cell lines.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    AZ'6421 is a Protcolysis Targeting Chimera (PROTAC) to selectively degrade estrogen receptor, shows ER binding and ER degradation with IC50 and DC50 values of 0.6 nM and 0.4 nM, respectively in MCF-7 cell lines.

    物理化学性质&存储条件

    分子量 975.17
    分子式 C52H65F3N6O7S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    参考文献

    1. Patent WO2019123367A1.

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