Chemical Structure : ARC-3140
货号: PC-22273Not For Human Use, Lab Use Only.
ARC-3140 is a potent, selective bisubstrate inhibitor of protein kinase CK2 (Casein kinase II) with Ki of 84 pM, addressing the ATP site and the substrate-binding site of CK2, interferes with both sub-interfaces of the bipartite CK2α/CK2β interaction.
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ARC-3140 is a potent, selective bisubstrate inhibitor of protein kinase CK2 (Casein kinase II) with Ki of 84 pM, addressing the ATP site and the substrate-binding site of CK2, interferes with both sub-interfaces of the bipartite CK2α/CK2β interaction.
分子量 | 1582.63 | |
分子式 | C45H58I4N10O21 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
1. Markus Pietsch, et al. Bioorg Chem. 2020 Mar:96:103608.
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