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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Parasite-AR102
AR102

Chemical Structure : AR102

CAS No.: 3021566-15-1

AR102 (AR-102)

货号: PC-23225Not For Human Use, Lab Use Only.

AR102 is a potent, selective, and broad-spectrum activity against schistosome species.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

AR102 is a potent, selective, and broad-spectrum activity against schistosome species.
AR102 is a potent antischistosomal with ED50 values of 7.8 and 18 mg/kg against the adult and juvenile stages of S. mansoni in infected mice and ED50 values of 8.5 and 6.3 mg/kg against adult S. haematobium in infected hamsters and adult S. japonicum in infected mice, respectively.

物理化学性质&存储条件

分子量 292.29
分子式 C13H7D6F3N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(3-(1,1-difluoroethyl)-4-fluorophenyl)-5,5-bis(methyl-d3)imidazolidine-2,4-dione

参考文献

1. Leas DA, et al. ACS Infect Dis. 2024 Oct 18. doi: 10.1021/acsinfecdis.4c00677.

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