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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Fungal-APX2039
APX2039

Chemical Structure : APX2039

CAS No.: 2342606-49-7

APX2039 (APX-2039)

货号: PC-23299Not For Human Use, Lab Use Only.

APX2039 is a novel potent small molecule inhibitor of fungal Gwt1, has MIC of 0.008-0.031 ug/ mL against C. neoformans, C. gattii, Candida albicans.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

APX2039 is a novel potent small molecule inhibitor of fungal Gwt1, has MIC of 0.008-0.031 ug/ mL against C. neoformans, C. gattii, Candida albicans.

物理化学性质&存储条件

分子量 362.36
分子式 C20H15FN4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-[3-[[4-[(6-Fluoro-2-pyridinyl)oxy]phenyl]methyl]-5-isoxazolyl]-2-pyridinamine

参考文献

1. Giamberardino CD, et al. mBio. 2022 Dec 20;13(6):e0234722.

2. Yu CH, et al.mBio. 2021 Dec 21;12(6):e0231321.

3. Karen Joy Shaw, et al. Antimicrob Agents Chemother. 2018 Jul 27;62(8):e00523-18.

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