Chemical Structure : APX2039
CAS No.: 2342606-49-7
货号: PC-23299Not For Human Use, Lab Use Only.
APX2039 is a novel potent small molecule inhibitor of fungal Gwt1, has MIC of 0.008-0.031 ug/ mL against C. neoformans, C. gattii, Candida albicans.
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APX2039 is a novel potent small molecule inhibitor of fungal Gwt1, has MIC of 0.008-0.031 ug/ mL against C. neoformans, C. gattii, Candida albicans.
分子量 | 362.36 | |
分子式 | C20H15FN4O2 | |
外观性状 | Solid | |
储存条件 |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
3-[3-[[4-[(6-Fluoro-2-pyridinyl)oxy]phenyl]methyl]-5-isoxazolyl]-2-pyridinamine |
1. Giamberardino CD, et al. mBio. 2022 Dec 20;13(6):e0234722.
2. Yu CH, et al.mBio. 2021 Dec 21;12(6):e0231321.
3. Karen Joy Shaw, et al. Antimicrob Agents Chemother. 2018 Jul 27;62(8):e00523-18.
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