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首页-小分子抑制剂&激动剂-GPCR-Sigma Receptor-ANAVEX2-73
ANAVEX2-73

Chemical Structure : ANAVEX2-73

CAS No.: 195615-84-0

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ANAVEX2-73 (Blarcamesine hydrochloride, ANAVEX 2-73)

货号: PC-38233Not For Human Use, Lab Use Only.

ANAVEX2-73 (Blarcamesine) hydrochloride is a potent Sigma-1 receptor agonist with IC50 of 860 nM, and muscarinic receptor modulator with neuroprotective effects.

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10 mg ￥980 In stock
25 mg ￥1580 In stock
50 mg ￥2580 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ANAVEX2-73 (Blarcamesine) hydrochloride is a potent Sigma-1 receptor agonist with IC50 of 860 nM, and muscarinic receptor modulator with neuroprotective effects.

物理化学性质&存储条件

分子量 317.857
分子式 C19H24ClNO
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Tetrahydro-N, N-dimethyl-2, 2-diphenyl-3-furanmethanamine hydrochloride

参考文献

1. Lahmy V, et al. Neuropsychopharmacology. 2013 Aug;38(9):1706-23. 

2. Lahmy V, et al. Front Cell Neurosci. 2015 Jan 20;8:463.

3. Kaufmann WE, et al. Pharmacol Biochem Behav. 2019 Dec;187:172796.

4. Ye N, et al. J Med Chem. 2020 Dec 24;63(24):15187-15217.

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