ALE-0540 |CAS:234779-34-1 Probechem Biochemicals

Chemical Structure : ALE-0540

CAS No.: 234779-34-1

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ALE-0540 (ALE0540)

货号: PC-61913Not For Human Use, Lab Use Only.

ALE-0540 is a nerve growth factor (NGF) antagonist that inhibits the binding of NGF to TrkA or both p75 and TrkA with IC50 of 5.88 and 3.72 uM, respectively.

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5 mg	￥1380	In stock
10 mg	￥2180	In stock
25 mg	￥3680	In stock
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100 mg		Get quote

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生物&药学活性

ALE-0540 (ALE0540) is a nerve growth factor (NGF) antagonist that inhibits the binding of NGF to TrkA or both p75 and TrkA with IC50 of 5.88 and 3.72 uM, respectively.
ALE-0540 produces antiallodynic actions in models of neuropathic pain.

物理化学性质&存储条件

分子量	301.258
分子式	C14H11N3O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(2-Hydroxyethylamino)-5-nitrobenzo[de]isoquinoline-1,3-dione

参考文献

1. Owolabi JB, et al. J Pharmacol Exp Ther. 1999 Jun;289(3):1271-6.

2. Eibl JK, et al. Eur J Pharmacol. 2013 May 15;708(1-3):30-7.

3. Sheffield KS, et al. Pharmacol Res. 2016 Jan;103:292-9.

ALE-0540 (ALE0540)

生物&药学活性

物理化学性质&存储条件

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ALE-0540 (ALE0540)

生物&药学活性

物理化学性质&存储条件

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