ACT-1016-0707

Chemical Structure : ACT-1016-0707

CAS No.: 2569467-78-1

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货号: PC-21751Not For Human Use, Lab Use Only.

ACT-1016-0707 is a potent, selective, and orally active lysophosphatidic acid receptor subtype 1 receptor (LPA1 receptor, LPAR1) antagonist with IC50 of 3.1 nM, highly selective over LPAR2 or LPAR3.

规格	价格	库存
5 mg	￥1380	In stock
10 mg	￥2180	In stock
25 mg	￥3880	In stock
50 mg		Get quote
100 mg		Get quote

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ACT-1016-0707 is a potent, selective, and orally active lysophosphatidic acid receptor subtype 1 receptor (LPA1 receptor, LPAR1) antagonist with IC50 of 3.1 nM, highly selective over LPAR2 or LPAR3.
ACT-1016-0707 suppressed the LPA-induced vascular leakage at a p.o. dose of 30 mg/kg.

物理化学性质&存储条件

分子量	438.93
分子式	C19H23ClN4O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(6-Chloro-4-methoxypyridin-3-yl)-3-(2-isopropylphenyl)-1-sulfamoylazetidine-3-carboxamide

参考文献

1. Lescop C, et al. J Med Chem. 2024 Feb 13. doi: 10.1021/acs.jmedchem.3c01827.

ACT-1016-0707

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