AC-260584 |CAS:560083-42-3 Probechem Biochemicals

Chemical Structure : AC-260584

CAS No.: 560083-42-3

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AC-260584 (AC260584)

货号: PC-42101Not For Human Use, Lab Use Only.

AC-260584 is a potent, selective, allosteric muscarinic M1 receptor agonist with pEC50 of 8.1, 7.6, 8.3 and 6.6 for WT M1, TM3 mutant W101A, L102A, and Y106A, repespectively.

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生物&药学活性

AC-260584 is a potent, selective, allosteric muscarinic M1 receptor agonist with pEC50 of 8.1, 7.6, 8.3 and 6.6 for WT M1, TM3 mutant W101A, L102A, and Y106A, repespectively.
AC-260584 increases acetylcholine and dopamine release in rat medial prefrontal cortex and hippocampus.

物理化学性质&存储条件

分子量	348.4549
分子式	C20H29FN2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2H-1,4-Benzoxazin-3(4H)-one, 4-[3-(4-butyl-1-piperidinyl)propyl]-7-fluoro-

参考文献

1. Li Z, et al. Eur J Pharmacol. 2007 Oct 31;572(2-3):129-37.

2. Spalding TA, et al. Mol Pharmacol. 2006 Dec;70(6):1974-83.

3. Li Z, et al. Eur J Pharmacol. 2008 Oct 31;596(1-3):89-97.

AC-260584 (AC260584)

生物&药学活性

物理化学性质&存储条件

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AC-260584 (AC260584)

生物&药学活性

物理化学性质&存储条件

参考文献

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