4-BBPB |CAS:201216-39-9 Probechem Biochemicals

Chemical Structure : 4-BBPB

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4-BBPB (BBPB)

货号: PC-61602Not For Human Use, Lab Use Only.

4-BBPB is a highly potent agonist of sigma 1 receptor (σ1 receptor) with Ki of 0.8 nM.

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生物&药学活性

4-BBPB is a highly potent agonist of sigma 1 receptor (σ1 receptor) with Ki of 0.8 nM.
4-BBPB attenuates activity of neuronal nitric oxide synthase (nNOS), blunts ischemia-induced nitric oxide production, and provides neuroprotection in stroke models.

物理化学性质&存储条件

分子量	293.454
分子式	C21H27N
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-phenyl-1-(4-phenylbutyl) piperidine

参考文献

1. Takahashi H, et al. Stroke. 1995 Sep;26(9):1676-82.

2. Narita N, et al. Eur J Pharmacol. 1995 Oct 6;293(3):277-80.

3. Yang ZJ, et al. Exp Neurol. 2010 Jan;221(1):166-74.

4-BBPB (BBPB)

生物&药学活性

物理化学性质&存储条件

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4-BBPB (BBPB)

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物理化学性质&存储条件

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