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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Fungal-1-ECBC
1-ECBC

Chemical Structure : 1-ECBC

CAS No.: 72755-19-2

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1-ECBC (Kumujian A, 1-Ethoxycarbonyl-β-carboline)

货号: PC-73393Not For Human Use, Lab Use Only.

1-ECBC is a small molecule inhibiting C. albicans filamentation, 1-ABC targets DYRK1-family kinase Yak1, the sole DYRK-family member expressed in C. albicans.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

1-ECBC is a small molecule inhibiting C. albicans filamentation, 1-ABC targets DYRK1-family kinase Yak1, the sole DYRK-family member expressed in C. albicans.
1-ECBC blocked C. albicans biofilm formation in several co-culture models and a rat catheter infection model.

物理化学性质&存储条件

分子量 240.262
分子式 C14H12N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-ethoxycarbonyl-beta-carboline

参考文献

1. MacAlpine J, et al. Nat Commun. 2021 Oct 22;12(1):6151.

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