1-ABC | Yak1 inhibitor | Probechem Biochemicals

Chemical Structure : 1-ABC

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1-ABC (C. albicans Yak1 inhibitor, 1-Acetyl-beta-carboline)

货号: PC-73392Not For Human Use, Lab Use Only.

1-ABC is a small molecule inhibiting C. albicans filamentation, 1-ABC targets DYRK1-family kinase Yak1, the sole DYRK-family member expressed in C. albicans.

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生物&药学活性

1-ABC is a small molecule inhibiting C. albicans filamentation, 1-ABC targets DYRK1-family kinase Yak1, the sole DYRK-family member expressed in C. albicans.
Single amino acid substitutions in the putative phosphatase Oca6 and in the transcription factor Rob1 could bypass the filamentation-repressive effects of 1-ABC.

物理化学性质&存储条件

分子量	210.236
分子式	C13H10N2O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(9H-pyrido[3,4-b]indol-1-yl)ethan-1-one

参考文献

1. MacAlpine J, et al. Nat Commun. 2021 Oct 22;12(1):6151.

1-ABC (C. albicans Yak1 inhibitor, 1-Acetyl-beta-carboline)

生物&药学活性

物理化学性质&存储条件

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1-ABC (C. albicans Yak1 inhibitor, 1-Acetyl-beta-carboline)

生物&药学活性

物理化学性质&存储条件

参考文献

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