(S)-dHTC1

Chemical Structure : (S)-dHTC1

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货号: PC-25534Not For Human Use, Lab Use Only.

(S)-dHTC1 is a potent, selective, and stereochemistry-dependent degrader of Eleven-Nineteen-Leukemia protein (ENL) with binding Kd of 49 nM for ENL.

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(S)-dHTC1 is a potent, selective, and stereochemistry-dependent degrader of Eleven-Nineteen-Leukemia protein (ENL) with binding Kd of 49 nM for ENL.

分子量	676.79
分子式	C33H40N8O6S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-N-cyclobutyl-2-(3-((2-(4-((6,8-dioxo-2,7-diazaspiro[4.4]nonane)-2-sulfonamido)piperidin-1-yl)ethyl)carbamoyl)phenyl)imidazo[1,2-a]pyridine-6-carboxamide

1. Shaum JB, et al. bioRxiv [Preprint]. 2025 Sep 4:2024.09.30.615685.