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首页-小分子抑制剂&激动剂-GPCR-Calcium-sensing Receptor (CaSR)-(S)-AC-265347
(S)-AC-265347

Chemical Structure : (S)-AC-265347

CAS No.: 1253901-30-2

(S)-AC-265347 ((S)-AC265347)

货号: PC-20137Not For Human Use, Lab Use Only.

(S)-AC-265347 is a potent, selective CaSR agonist and positive allosteric modulator (ago-PAM), 10- to 20-fold more potent than (R)-AC-265347.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    (S)-AC-265347 is a potent, selective CaSR agonist and positive allosteric modulator (ago-PAM), 10- to 20-fold more potent than (R)-AC-265347.

    物理化学性质&存储条件

    分子量 283.39
    分子式 C17H17NOS
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (S)-1-(benzo[d]thiazol-2-yl)-1-(2,4-dimethylphenyl)ethan-1-ol

    参考文献

    1. Ma JN, et al. J Pharmacol Exp Ther. 2011 Apr;337(1):275-84.

    2. Cook AE, et al. Br J Pharmacol. 2015 Jan;172(1):185-200.

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